Neuronal Control of Bone Remodeling
نویسندگان
چکیده
منابع مشابه
Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling.
The CB1 cannabinoid receptor has been implicated in the regulation of bone remodeling and bone mass. A high bone mass (HBM) phenotype was reported in CB1-null mice generated on a CD1 background (CD1(CB1-/-) mice). By contrast, our preliminary studies in cb1-/- mice, backcrossed to C57BL/6J mice (C57(CB1-/-) mice), revealed low bone mass (LBM). We therefore analyzed CB1 expression in bone and co...
متن کاملACCELERATED COMMUNICATION Involvement of Neuronal Cannabinoid Receptor CB1 in Regulation of Bone Mass and Bone Remodeling
The CB1 cannabinoid receptor has been implicated in the regulation of bone remodeling and bone mass. A high bone mass (HBM) phenotype was reported in CB1-null mice generated on a CD1 background (CD1 / mice). By contrast, our preliminary studies in cb1 / mice, backcrossed to C57BL/6J mice (C57 / mice), revealed low bone mass (LBM). We therefore analyzed CB1 expression in bone and compared the sk...
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During the last fifteen years, an increasing number of studies have examined the origin, the ontogeny, and the distribution of nerve fibers in bone. They have also investigated the nature of neuromediators conveyed by these skeletal nerve fibers. Experimental models of sensory and sympathetic denervation and clinical studies have shown that these two neuronal systems are involved in bone develo...
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15 صفحه اولBone Remodeling and Healing
To fulfill adequately their functions of support, sustentation and protection for the internal organs and guarantee blood calcium homeostasis, bone tissue is in constant remodeling. Alveolar bone, the primary support structure for teeth, is particularly subjected to continuous and fast remodeling associated with tooth eruption and positional adaptations, as well as with the functional demands o...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 2017
ISSN: 0192-6233,1533-1601
DOI: 10.1177/0192623317738708